{"id":26,"date":"2022-06-15T18:00:37","date_gmt":"2022-06-15T15:00:37","guid":{"rendered":"http:\/\/lmd.impb.ru\/wordpress\/?page_id=26"},"modified":"2022-06-15T18:13:30","modified_gmt":"2022-06-15T15:13:30","slug":"%d0%9b%d0%b8%d1%85%d0%b0%d1%87%d1%91%d0%b2-%d0%98%d0%bb%d1%8c%d1%8f-%d0%92%d1%8f%d1%87%d0%b5%d1%81%d0%bb%d0%b0%d0%b2%d0%be%d0%b2%d0%b8%d1%87","status":"publish","type":"page","link":"http:\/\/lmd.impb.ru\/wordpress\/%d0%a1%d0%be%d1%82%d1%80%d1%83%d0%b4%d0%bd%d0%b8%d0%ba%d0%b8\/%d0%9b%d0%b8%d1%85%d0%b0%d1%87%d1%91%d0%b2-%d0%98%d0%bb%d1%8c%d1%8f-%d0%92%d1%8f%d1%87%d0%b5%d1%81%d0%bb%d0%b0%d0%b2%d0%be%d0%b2%d0%b8%d1%87\/","title":{"rendered":"\u041b\u0438\u0445\u0430\u0447\u0451\u0432 \u0418\u043b\u044c\u044f \u0412\u044f\u0447\u0435\u0441\u043b\u0430\u0432\u043e\u0432\u0438\u0447"},"content":{"rendered":"\n
  1. \u041b\u0438\u0445\u0430\u0447\u0435\u0432 \u0418.\u0412., \u0411\u0430\u043b\u0430\u0431\u0430\u0435\u0432 \u041d.\u041a. \u0410\u043d\u0430\u043b\u0438\u0437\u0430\u0442\u043e\u0440 \u0442\u0440\u0430\u0435\u043a\u0442\u043e\u0440\u0438\u0439 \u043c\u043e\u043b\u0435\u043a\u0443\u043b\u044f\u0440\u043d\u043e\u0439 \u0434\u0438\u043d\u0430\u043c\u0438\u043a\u0438. \/\/ \u041c\u0430\u0442\u0435\u043c\u0430\u0442\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0431\u0438\u043e\u043b\u043e\u0433\u0438\u044f \u0438 \u0431\u0438\u043e\u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0442\u0438\u043a\u0430. 2007. \u0422. 2. \u2116 1. \u0421. 120-129.<\/li>
  2. \u041b\u0438\u0445\u0430\u0447\u0435\u0432 \u0418.\u0412., \u0411\u0430\u043b\u0430\u0431\u0430\u0435\u0432 \u041d.\u041a. \u0410\u043d\u0430\u043b\u0438\u0437\u0430\u0442\u043e\u0440 \u0442\u0440\u0430\u0435\u043a\u0442\u043e\u0440\u0438\u0439 \u043c\u043e\u043b\u0435\u043a\u0443\u043b\u044f\u0440\u043d\u043e\u0439 \u0434\u0438\u043d\u0430\u043c\u0438\u043a\u0438 (TAMD) \/\/ \u0421\u0432\u0438\u0434\u0435\u0442\u0435\u043b\u044c\u0441\u0442\u0432\u043e \u043e \u0433\u043e\u0441\u0443\u0434\u0430\u0440\u0441\u0442\u0432\u0435\u043d\u043d\u043e\u0439 \u0440\u0435\u0433\u0438\u0441\u0442\u0440\u0430\u0446\u0438\u0438 \u043f\u0440\u043e\u0433\u0440\u0430\u043c\u043c\u044b \u0434\u043b\u044f \u042d\u0412\u041c \u2116 2014612313.<\/li>
  3. \u041b\u0438\u0445\u0430\u0447\u0435\u0432 \u0418.\u0412., \u0411\u0430\u043b\u0430\u0431\u0430\u0435\u0432 \u041d.\u041a. \u041f\u043e\u0441\u0442\u0440\u043e\u0435\u043d\u0438\u0435 \u0440\u0430\u0441\u0448\u0438\u0440\u0435\u043d\u043d\u044b\u0445 \u0434\u0438\u043d\u0430\u043c\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u043a\u043e\u043d\u0442\u0430\u043a\u0442\u043d\u044b\u0445 \u043a\u0430\u0440\u0442 \u043f\u043e \u0434\u0430\u043d\u043d\u044b\u043c \u043c\u043e\u043b\u0435\u043a\u0443\u043b\u044f\u0440\u043d\u043e-\u0434\u0438\u043d\u0430\u043c\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u0440\u0430\u0441\u0447\u0435\u0442\u043e\u0432. \/\/ \u041c\u0430\u0442\u0435\u043c\u0430\u0442\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0431\u0438\u043e\u043b\u043e\u0433\u0438\u044f \u0438 \u0431\u0438\u043e\u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0442\u0438\u043a\u0430. 2009. \u0422. 4. \u2116 1. \u0421. 36-45.<\/li>
  4. \u0411\u0430\u0441\u043e\u0432\u0430 \u041e.\u041d., \u041b\u0438\u0445\u0430\u0447\u0435\u0432 \u0418.\u0412. PMS-Diagnostic \/\/ \u0421\u0432\u0438\u0434\u0435\u0442\u0435\u043b\u044c\u0441\u0442\u0432\u043e \u043e \u0433\u043e\u0441\u0443\u0434\u0430\u0440\u0441\u0442\u0432\u0435\u043d\u043d\u043e\u0439 \u0440\u0435\u0433\u0438\u0441\u0442\u0440\u0430\u0446\u0438\u0438 \u043f\u0440\u043e\u0433\u0440\u0430\u043c\u043c\u044b \u0434\u043b\u044f \u042d\u0412\u041c \u2116 2012613364.<\/li>
  5. \u00a0Glyakina AV, Likhachev IV, Balabaev NK, Galzitskaya OV. Right- and left-handed three-helix proteins. II. Similarity and differences in mechanical unfolding of proteins. \/\/ Proteins. 2014. V. 82. No. 1. P. 90-102.<\/li>
  6. \u041b\u0438\u0445\u0430\u0447\u0435\u0432 \u0418.\u0412., \u0413\u0430\u043b\u0437\u0438\u0442\u0441\u043a\u0430\u044f \u041e.\u0412., \u0411\u0430\u043b\u0430\u0431\u0430\u0435\u0432 \u041d.\u041a. \u0418\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435 \u043c\u0435\u0445\u0430\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u0441\u0432\u043e\u0439\u0441\u0442\u0432 C-\u043a\u0430\u0434\u0433\u0435\u0440\u0438\u043d\u0430 \u043c\u0435\u0442\u043e\u0434\u043e\u043c \u043c\u043e\u043b\u0435\u043a\u0443\u043b\u044f\u0440\u043d\u043e\u0439 \u0434\u0438\u043d\u0430\u043c\u0438\u043a\u0438. \/\/ \u041a\u043e\u043c\u043f\u044c\u044e\u0442\u0435\u0440\u043d\u044b\u0435 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f \u0438 \u043c\u043e\u0434\u0435\u043b\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u0435. 2013. \u0422. 5. \u2116 4. \u0421. 727-735.<\/li>
  7. \u041b\u0438\u0445\u0430\u0447\u0435\u0432 \u0418.\u0412., \u0413\u043b\u044f\u043a\u0438\u043d\u0430 \u0410.\u0412., \u0413\u0430\u043b\u0437\u0438\u0442\u0441\u043a\u0430\u044f \u041e.\u0412., \u0411\u0430\u043b\u0430\u0431\u0430\u0435\u0432 \u041d.\u041a. \u0410\u043d\u0430\u043b\u0438\u0437\u0430\u0442\u043e\u0440 \u0442\u0440\u0430\u0435\u043a\u0442\u043e\u0440\u0438\u0439 \u043c\u043e\u043b\u0435\u043a\u0443\u043b\u044f\u0440\u043d\u043e\u0439 \u0434\u0438\u043d\u0430\u043c\u0438\u043a\u0438 \u0438 \u0435\u0433\u043e \u043f\u0440\u0438\u043c\u0435\u043d\u0435\u043d\u0438\u0435 \u043a \u0438\u0437\u0443\u0447\u0435\u043d\u0438\u044e \u043c\u0435\u0445\u0430\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u0441\u0432\u043e\u0439\u0441\u0442\u0432 \u0431\u0435\u043b\u043a\u043e\u0432. \/\/ CUDA-\u0430\u043b\u044c\u043c\u0430\u043d\u0430\u0445 \u0437\u0430 \u043e\u043a\u0442\u044f\u0431\u0440\u044c 2014.<\/li>
  8. Glyakina AV, Likhachev IV, Balabaev NK, Galzitskaya OV. Mechanical stability analysis of the protein L immunoglobulin-binding domain by full alanine screening using molecular dynamics simulations. Biotechnol J. 2015 Mar;10(3):386-94. doi: 10.1002\/biot.201400231. Epub 2015 Jan 16. PubMed PMID: 25425165.<\/li>
  9. \u041b\u0438\u0445\u0430\u0447\u0435\u0432 \u0418.\u0412. \u0410\u0432\u0442\u043e\u0440\u0435\u0444\u0435\u0440\u0430\u0442 \u0434\u0438\u0441\u0441\u0435\u0440\u0442\u0430\u0446\u0438\u0438 \u00ab\u0410\u043d\u0430\u043b\u0438\u0437\u0430\u0442\u043e\u0440 \u0442\u0440\u0430\u0435\u043a\u0442\u043e\u0440\u0438\u0439 \u043c\u043e\u043b\u0435\u043a\u0443\u043b\u044f\u0440\u043d\u043e\u0439 \u0434\u0438\u043d\u0430\u043c\u0438\u043a\u0438 \u0438 \u0435\u0433\u043e \u043f\u0440\u0438\u043c\u0435\u043d\u0435\u043d\u0438\u0435 \u043a \u0438\u0437\u0443\u0447\u0435\u043d\u0438\u044e \u043c\u0435\u0445\u0430\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u0441\u0432\u043e\u0439\u0441\u0442\u0432 \u0431\u0435\u043b\u043a\u043e\u0432\u00bb. 2014<\/li>
  10. \u041b\u0438\u0445\u0430\u0447\u0435\u0432 \u0418.\u0412. \u0414\u0438\u0441\u0441\u0435\u0440\u0442\u0430\u0446\u0438\u044f \u00ab\u0410\u043d\u0430\u043b\u0438\u0437\u0430\u0442\u043e\u0440 \u0442\u0440\u0430\u0435\u043a\u0442\u043e\u0440\u0438\u0439 \u043c\u043e\u043b\u0435\u043a\u0443\u043b\u044f\u0440\u043d\u043e\u0439 \u0434\u0438\u043d\u0430\u043c\u0438\u043a\u0438 \u0438 \u0435\u0433\u043e \u043f\u0440\u0438\u043c\u0435\u043d\u0435\u043d\u0438\u0435 \u043a \u0438\u0437\u0443\u0447\u0435\u043d\u0438\u044e \u043c\u0435\u0445\u0430\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u0441\u0432\u043e\u0439\u0441\u0442\u0432 \u0431\u0435\u043b\u043a\u043e\u0432\u00bb. 2014<\/li>
  11. Glyakina A.V., Likhachev I.V., Balabaev N.K., Galzitskaya O.V. Mechanical stability analysis of the protein L immunoglobulin-binding domain by full alanine screening using molecular dynamics simulations. Biotechnol J. 2015 Mar;10(3):386-94. doi: 10.1002\/biot.201400231. Epub 2015 Jan 16.<\/li>
  12. Likhachev I.V., Balabaev N.K., Galzitskaya O.V. Available Instruments for Analyzing Molecular Dynamics Trajectories. The Open Biochemistry Journal, 2016, 10: 1-11.<\/li>
  13. Glyakina A.V., Likhachev I.V., Balabaev N.K., Galzitskaya O.V. Comparative mechanical unfolding studies of spectrin domains R15, R16 and R17. J Struct Biol. 2018 Feb;201(2):162-170. doi: 10.1016\/j.jsb.2017.12.003. Epub 2017 Dec 5.<\/li>
  14. \u041b\u0438\u0445\u0430\u0447\u0435\u0432 \u0418.\u0412., \u0411\u0430\u043b\u0430\u0431\u0430\u0435\u0432 \u041d.\u041a. \u0418\u0441\u043f\u043e\u043b\u044c\u0437\u043e\u0432\u0430\u043d\u0438\u0435 \u043f\u0430\u0440\u0430\u043b\u043b\u0435\u043b\u0438\u0437\u043c\u0430 \u0440\u0430\u0437\u043b\u0438\u0447\u043d\u044b\u0445 \u0443\u0440\u043e\u0432\u043d\u0435\u0439 \u0432 \u043f\u0440\u043e\u0433\u0440\u0430\u043c\u043c\u0435 \u043c\u043e\u0434\u0435\u043b\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u044f \u043c\u043e\u043b\u0435\u043a\u0443\u043b\u044f\u0440\u043d\u043e\u0439 \u0434\u0438\u043d\u0430\u043c\u0438\u043a\u0438 PUMA-CUDA. \u0414\u043e\u043a\u043b\u0430\u0434\u044b \u041c\u0435\u0436\u0434\u0443\u043d\u0430\u0440\u043e\u0434\u043d\u043e\u0439 \u043a\u043e\u043d\u0444\u0435\u0440\u0435\u043d\u0446\u0438\u0438 «\u041c\u0430\u0442\u0435\u043c\u0430\u0442\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0431\u0438\u043e\u043b\u043e\u0433\u0438\u044f \u0438 \u0431\u0438\u043e\u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0442\u0438\u043a\u0430». \u041f\u043e\u0434 \u0440\u0435\u0434. \u0412.\u0414. \u041b\u0430\u0445\u043d\u043e. \u0422\u043e\u043c 7. \u041f\u0443\u0449\u0438\u043d\u043e: \u0418\u041c\u041f\u0411 \u0420\u0410\u041d, 2018. \u0421\u0442\u0430\u0442\u044c\u044f \u2116 e44. doi: 10.17537\/icmbb18.53<\/li>
  15. \u041b\u0438\u0445\u0430\u0447\u0435\u0432 \u0418.\u0412., \u041b\u0430\u0445\u043d\u043e \u0412.\u0414. \u041d\u0430\u0437\u0432\u0430\u043d\u0438\u0435: \u0418\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435 \u0434\u0435\u043d\u0430\u0442\u0443\u0440\u0430\u0446\u0438\u0438 \u0414\u041d\u041a \u043d\u0430 \u043e\u0441\u043d\u043e\u0432\u0435 \u043c\u043e\u0434\u0435\u043b\u0438 \u041f\u0435\u0439\u0440\u0430\u0440\u0434\u0430-\u0411\u0438\u0448\u043e\u043f\u0430-\u0414\u043e\u043a\u0441\u0443\u0430 \u043c\u0435\u0442\u043e\u0434\u043e\u043c \u043c\u043e\u043b\u0435\u043a\u0443\u043b\u044f\u0440\u043d\u043e\u0439 \u0434\u0438\u043d\u0430\u043c\u0438\u043a\u0438. \u041f\u0440\u0435\u043f\u0440\u0438\u043d\u0442 \u0418\u041f\u041c \u2116 232, \u041c\u043e\u0441\u043a\u0432\u0430, 2018<\/li>
  16. \u0410\u043d\u0434\u0440\u0435\u0435\u0432 \u0421.\u0421., \u0414\u0431\u0430\u0440 \u0421.\u0410., \u041b\u0430\u0446\u0438\u0441 \u0410.\u041e., \u041b\u0438\u0445\u0430\u0447\u0435\u0432 \u0418. \u0412., \u041f\u043b\u043e\u0442\u043a\u0438\u043d\u0430 \u0415.\u0410., \u0424\u0438\u0430\u043b\u043a\u043e \u041d.\u0421. \u0422\u0438\u043f\u043e\u0432\u0430\u044f \u0441\u0442\u0440\u0443\u043a\u0442\u0443\u0440\u0430 \u043f\u0440\u043e\u0433\u0440\u0430\u043c\u043c\u044b \u043e\u0434\u043d\u043e\u043c\u0435\u0440\u043d\u043e\u0433\u043e \u043c\u043e\u0434\u0435\u043b\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u044f \u0434\u0438\u043d\u0430\u043c\u0438\u043a\u0438 \u0446\u0435\u043f\u043e\u0447\u043a\u0438 \u0414\u041d\u041a \u0438 \u0435\u0435 \u0441\u0445\u0435\u043c\u043d\u0430\u044f \u0440\u0435\u0430\u043b\u0438\u0437\u0430\u0446\u0438\u044f. \u041f\u0440\u0435\u043f\u0440\u0438\u043d\u0442 \u0418\u041f\u041c \u2116 171, \u041c\u043e\u0441\u043a\u0432\u0430, 2018.<\/li>
  17. I.V. Likhachev<\/a>, V.D. Lakhno<\/a>. Investigation of DNA denaturation in Peyrard-Bishop-Dauxois model by molecular dynamics method. arXive.org. arXiv:1811.03405, arXiv:1811.03405v1.<\/li>
  18. I.V. Likhachev, V.D. Lakhno. The direct investigation of DNA denaturation in Peyrard-Bishop-Dauxois model by molecular dynamics method. Chemical Physics Letters 727 (2019) 55\u201358.<\/li>
  19. I.V. Likhachev, V.D. Lakhno. Investigation of DNA denaturation in Peyrard-Bishop-Dauxoismodel by molecular dynamics method. Eur. Phys. J. B (2019) 92: 253. DOI:10.1140\/epjb\/e2019-90741-6.<\/li>
  20. Likhachev, I.V., Balabaev, N.K., Galzitskaya, O.V., 2020. Elastic and Non-elastic Properties of Cadherin Ectodomain: Comparison with Mechanical System. Advances in Computer Science for Engineering and Education II, Advances in Intelligent Systems and Computing. Springer International Publishing, Cham, pp. 555\u2013566. https:\/\/doi.org\/10.1007\/978-3-030-16621-2_52 (\u0411\u0435\u0437 \u0433\u0440\u0430\u043d\u0442\u043e\u0432). \u0411\u0435\u0437 \u043a\u0432\u0430\u0440\u0442\u0438\u043b\u044f.<\/li>
  21. Michail Yu. Lobanov, Ilya V. Likhachev, Oxana Galzitskaya. Disordered Residues and Patterns in the Protein Data Bank. Molecules. 2020 Apr; 25(7): 1522. doi: 10.3390\/molecules25071522. \u041a\u0432\u0430\u0440\u0442\u0438\u043b\u044c: \u043d\u0430\u0432\u0435\u0440\u043d\u043e\u0435, Q3, \u043d\u043e \u044f \u043d\u0435 \u0443\u0432\u0435\u0440\u0435\u043d. \u0423 \u0436\u0443\u0440\u043d\u0430\u043b\u0430 \u043d\u0435\u0441\u043a\u043e\u043b\u044c\u043a\u043e \u043a\u0432\u0430\u0440\u0442\u0438\u043b\u0435\u0439. https:\/\/www.scimagojr.com\/journalsearch.php?q=26370&tip=sid&clean=0<\/li>
  22. \u0428\u0438\u0433\u0430\u0435\u0432 \u0410.\u0421., \u041b\u0438\u0445\u0430\u0447\u0451\u0432 \u0418.\u0412., \u041b\u0430\u0445\u043d\u043e \u0412.\u0414. \u0418\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435 \u043c\u043e\u0434\u0435\u043b\u0438 \u0414\u041d\u041a \u0441 \u043d\u0435\u043b\u043e\u043a\u0430\u043b\u044c\u043d\u043e\u0439 \u0441\u0432\u044f\u0437\u044c\u044e \u0432 \u0441\u0442\u043e\u043b\u043a\u043d\u043e\u0432\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u043c \u0442\u0435\u0440\u043c\u043e\u0441\u0442\u0430\u0442\u0435 \u041c\u0430\u0442\u0435\u043c\u0430\u0442\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0431\u0438\u043e\u043b\u043e\u0433\u0438\u044f \u0438 \u0431\u0438\u043e\u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0442\u0438\u043a\u0430. 2020;15(2):129-137. doi: 10.17537\/2020.15.129. \u0412\u0410\u041a, \u0420\u0418\u041d\u0426, Scopus.<\/li>
  23. \u041b\u0438\u0445\u0430\u0447\u0435\u0432 \u0418.\u0412., \u0411\u044b\u0441\u0442\u0440\u043e\u0432 \u0412.\u0421. \u0421\u0431\u043e\u0440\u043a\u0430 \u0444\u0435\u043d\u0438\u043b\u0430\u043b\u0430\u043d\u0438\u043d\u043e\u0432\u043e\u0439 \u043d\u0430\u043d\u043e\u0442\u0440\u0443\u0431\u043a\u0438 \u043c\u043e\u043b\u0435\u043a\u0443\u043b\u044f\u0440\u043d\u043e-\u0434\u0438\u043d\u0430\u043c\u0438\u0447\u0435\u0441\u043a\u0438\u043c \u043c\u0430\u043d\u0438\u043f\u0443\u043b\u044f\u0442\u043e\u0440\u043e\u043c. \u041c\u0430\u0442\u0435\u043c\u0430\u0442\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0431\u0438\u043e\u043b\u043e\u0433\u0438\u044f \u0438 \u0431\u0438\u043e\u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0442\u0438\u043a\u0430. 2021; 16(2): 244-255. doi: 10.17537\/2021.16.244. \u0412\u0410\u041a, \u0420\u0418\u041d\u0426, Scopus.<\/li>
  24. Chirgadze YN, Battaile KP, Likhachev IV, Balabaev NK, Gordon RD, Romanov V, Lin A, Karisch R, Lam R, Ruzanov M, Brazhnikov EV, Pai EF, Neel BG, Chirgadze NY. Signal transfer in human protein tyrosine phosphatase PTP1B from allosteric inhibitor P00058. J Biomol Struct Dyn. 2021 Oct 27:1-10. doi: 10.1080\/07391102.2021.1994879. Epub ahead of print. PMID: 34705594.<\/li>
  25. Lobanov MY, Pereyaslavets LB, Likhachev IV, Matkarimov BT, Galzitskaya OV. Is there an advantageous arrangement of aromatic residues in proteins? Statistical analysis of aromatic interactions in globular proteins. Comput Struct Biotechnol J. 2021 Nov 1;19:5960-5968. doi: 10.1016\/j.csbj.2021.10.036. PMID: 34849200; PMCID: PMC8604681.<\/li>
  26. Sidorova, Alla, Vladimir Bystrov, Aleksey Lutsenko, Denis Shpigun, Ekaterina Belova, and Ilya Likhachev. 2021. «Quantitative Assessment of Chirality of Protein Secondary Structures and Phenylalanine Peptide Nanotubes» Nanomaterials 11, no. 12: 3299. https:\/\/doi.org\/10.3390\/nano11123299.<\/li><\/ol>\n","protected":false},"excerpt":{"rendered":"

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